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Aileron Therapeutics, Inc. is a U.S.-based clinical-stage company specializing in chemoprotection oncology. Its primary therapeutic candidate, ALRN-6924, is currently being evaluated across multiple clinical trials for various cancer types. These include a Phase 1 trial for solid tumors and lymphoma, a Phase 2a clinical trial targeting peripheral T-cell lymphoma, and a Phase I trial for acute myeloid leukemia (AML) and advanced myelodysplastic syndrome (MDS). Furthermore, ALRN-6924 is involved in combination studies: a Phase 1b trial testing its efficacy with cytarabine (Ara-C) in patients with MDS, and a Phase 2a combination trial with palbociclib for individuals with tumors exhibiting MDM2 amplifications co-amplifications, as well as for those with p53-mutated small cell lung cancer (the latter having already completed its Phase 1b clinical assessment). The company maintains license agreements with institutions such as the Dana-Farber Cancer Institute, Harvard College, and Umicore Precious Metals Chemistry USA, LLC. Established in 2001, the Boston, Massachusetts-headquartered firm was originally known as Renegade Therapeutics, Inc. before rebranding to Aileron Therapeutics, Inc. in February 2007.
Fri, 05 Jun 2026
Why Is Aileron Therapeutics, Inc. (ALRN) Stock Up Today? - Meyka
Thu, 24 Apr 2025
ALRN Stock Price, News & Analysis - Stock Titan
Fri, 10 Jan 2025
Aileron Therapeutics Announces Rebranding to Rein Therapeutics - PR Newswire
Thu, 14 Nov 2024
Aileron Therapeutics Reports Third Quarter 2024 Financial Results and Recent Business Highlights - PR Newswire
Fri, 10 Mar 2023
Early signals in Aileron Therapeutic's ALRN-6924 program hinted at a struggle for efficacy over a year before negative results - statnews.com
Wed, 22 Feb 2023
Cancer drugmaker down to 3 employees after trial failure - The Business Journals
| Price to Book Value: P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly. |
Neutral |
| Price to Earnings: PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS). |
Underperform |
| Discounted cash flow: DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows. |
Outperform |
| Return on Assets: ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit. |
Underperform |
| Return on Equity: ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency. |
Underperform |
| Debt to Equity: evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn. |
Underperform |
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NASDAQ
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Sector:
Healthcare
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Industry:
Biotechnology
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