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Bicycle Therapeutics plc (BCYC)
3.89  0.03 (0.78%)    09-14 16:00
Open: 3.86
High: 3.905
Volume: 209,372
  
Pre. Close: 3.86
Low: 3.83
Market Cap: 270(M)
Technical analysis
2026-09-14 4:35:37 PM
Short term     
Mid term     
Targets 6-month :  4.95 1-year :  5.26
Resists First :  4.24 Second :  4.51
Pivot price 4.16
Supports First :  3.81 Second :  3.17
MAs MA(5) :  3.95 MA(20) :  4.15
MA(100) :  4.28 MA(250) :  5.59
MACD MACD :  -0.1 Signal :  0
%K %D K(14,3) :  6.6 D(3) :  8.8
RSI RSI(14): 40.1
52-week High :  9.15 Low :  3.74
Price, MAs and Bollinger Bands

Price has closed below its short-term moving average. Short-term moving average is currently below mid-term; and below long-term moving average. From the relationship between price and moving averages: This stock is BEARISH in short-term; and BEARISH in mid-long term.
[ BCYC ] has closed above bottom band by 12.5%. Bollinger Bands are 23.6% wider than normal. The current width of the bands does not suggest anything about the future direction or movement of prices.

Stock Price Prediction
If tomorrow: Open lower Open higher
High: 3.91 - 3.93 3.93 - 3.95
Low: 3.78 - 3.81 3.81 - 3.83
Close: 3.85 - 3.89 3.89 - 3.92
Company Description

Bicycle Therapeutics plc, founded in 2009 and based in Cambridge, UK, is a clinical-stage biopharmaceutical company. Its core mission is to create innovative therapeutic classes for diseases currently lacking effective treatments. The company's leading investigational product, BT1718, is a Bicycle Toxin Conjugate (BTC) that is undergoing Phase I/IIa clinical trials. This candidate is engineered to target tumors specifically expressing Membrane Type 1 matrix metalloprotease. Other oncology assets in their pipeline include BT5528, also a BTC in Phase I/II studies, which targets EphA2, and BT8009, currently in Phase I/II clinical development, designed to target Nectin-4. Beyond cancer, Bicycle Therapeutics is advancing THR-149, a plasma kallikrein inhibitor that has completed Phase II clinical trials for the treatment of diabetic macular edema. Their portfolio also includes Bicycle tumor-targeted immune cell agonists (TICAs) such as BT7480, which targets Nectin-4, and BT7455, an EphA2/CD137 TICA presently in preclinical development. The company actively fosters collaborations with various biopharmaceutical entities and organizations, broadening its development efforts into therapeutic areas like anti-infectives, cardiovascular conditions, ophthalmology, and respiratory illnesses. Notable partnerships include a clinical trial and license agreement with Cancer Research Technology Limited and Cancer Research UK. They also maintain research collaborations with AstraZeneca, Sanofi, Oxurion, and the Dementia Discovery Fund. Furthermore, a significant discovery collaboration and license agreement with Genentech is in place for the identification and development of Bicycle peptides for multiple immuno-oncology targets.

Headline News

Sat, 22 Aug 2026
Possible Signal As Bicycle Therapeutics Insiders Sell US$523k In Stock - simplywall.st

Thu, 30 Jul 2026
Bicycle Therapeutics plc American (BCYC) EPS 2025: $3.16 loss per share, down 9.0% - Stock Titan

Thu, 30 Jul 2026
Bicycle Therapeutics PLC 2026: Revenue $629K, EPS ($0.72) — 10-Q Summary - TradingView

Thu, 30 Jul 2026
Bicycle Therapeutics Reports Recent Business Progress and Second Quarter 2026 Financial Results - BioSpace

Fri, 24 Jul 2026
Bicycle Therapeutics plc (BCYC) Stock Report: Exploring a 226% Potential Upside in the Biotechnology Sector - directorstalkinterviews.com

Fri, 17 Jul 2026
Bicycle Therapeutics (BCYC) awards 60,000 options to supply chain chief - Stock Titan

Financial Analysis
Price to Book Value:
P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly.
Outperform
Price to Earnings:
PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS).
Underperform
Discounted cash flow:
DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows.
Underperform
Return on Assets:
ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit.
Underperform
Return on Equity:
ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency.
Underperform
Debt to Equity:
evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn.
Outperform
Stock Basics & Statistics
Exchange:
NASDAQ
Sector:
Healthcare
Industry:
Biotechnology
Shares Out 0 (M)
Shares Float 51 (M)
Held by Insiders 0 (%)
Held by Institutions 4.4 (%)
Shares Short 2,980 (K)
Shares Short P.Month 0 (K)
Stock Financials
EPS -2.0081e+008
EPS Est Next Qtrly 0
EPS Est This Year 0
EPS Est Next Year 0
Book Value (p.s.) 0
Profit Margin 0 %
Operating Margin -8 %
Return on Assets (ttm) 673.9 %
Return on Equity (ttm) -18 %
Qtrly Rev. Growth 6.12e+007 %
Gross Profit (p.s.) -50.98
Sales Per Share -20.98
EBITDA (p.s.) -8.30195e+007
Qtrly Earnings Growth -2.8 %
Operating Cash Flow 0 (M)
Levered Free Cash Flow -206 (M)
Stock Valuations
PE Ratio -0.01
PEG Ratio 0
Price to Book value 0
Price to Sales -0.19
Price to Cash Flow 0.81
Stock Dividends
Dividend 0
Forward Dividend 3.22e+006
Dividend Yield 0%
Dividend Pay Date Invalid DateTime.
Ex-Dividend Date Invalid DateTime.

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