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Bicycle Therapeutics plc (BCYC)
4.05  -0.05 (-1.22%)    06-12 16:00
Open: 4.09
High: 4.1
Volume: 767,609
  
Pre. Close: 4.1
Low: 4.025
Market Cap: 281(M)
Technical analysis
2026-06-15 8:13:50 AM
Short term     
Mid term     
Targets 6-month :  5.33 1-year :  5.76
Resists First :  4.56 Second :  4.93
Pivot price 4.33
Supports First :  3.97 Second :  3.3
MAs MA(5) :  4.09 MA(20) :  4.35
MA(100) :  5.08 MA(250) :  6.46
MACD MACD :  -0.2 Signal :  -0.2
%K %D K(14,3) :  10.7 D(3) :  12.5
RSI RSI(14): 34.1
52-week High :  9.18 Low :  3.97
Price, MAs and Bollinger Bands

Price has closed below its short-term moving average. Short-term moving average is currently below mid-term; and below long-term moving average. From the relationship between price and moving averages: This stock is BEARISH in short-term; and BEARISH in mid-long term.
[ BCYC ] has closed above bottom band by 18.9%. Bollinger Bands are 10.8% narrower than normal. The current width of the bands does not suggest anything about the future direction or movement of prices.

Stock Price Prediction
If tomorrow: Open lower Open higher
High: 4.11 - 4.13 4.13 - 4.15
Low: 3.97 - 4 4 - 4.02
Close: 4.01 - 4.05 4.05 - 4.09
Company Description

Bicycle Therapeutics plc, founded in 2009 and based in Cambridge, UK, is a clinical-stage biopharmaceutical company. Its core mission is to create innovative therapeutic classes for diseases currently lacking effective treatments. The company's leading investigational product, BT1718, is a Bicycle Toxin Conjugate (BTC) that is undergoing Phase I/IIa clinical trials. This candidate is engineered to target tumors specifically expressing Membrane Type 1 matrix metalloprotease. Other oncology assets in their pipeline include BT5528, also a BTC in Phase I/II studies, which targets EphA2, and BT8009, currently in Phase I/II clinical development, designed to target Nectin-4. Beyond cancer, Bicycle Therapeutics is advancing THR-149, a plasma kallikrein inhibitor that has completed Phase II clinical trials for the treatment of diabetic macular edema. Their portfolio also includes Bicycle tumor-targeted immune cell agonists (TICAs) such as BT7480, which targets Nectin-4, and BT7455, an EphA2/CD137 TICA presently in preclinical development. The company actively fosters collaborations with various biopharmaceutical entities and organizations, broadening its development efforts into therapeutic areas like anti-infectives, cardiovascular conditions, ophthalmology, and respiratory illnesses. Notable partnerships include a clinical trial and license agreement with Cancer Research Technology Limited and Cancer Research UK. They also maintain research collaborations with AstraZeneca, Sanofi, Oxurion, and the Dementia Discovery Fund. Furthermore, a significant discovery collaboration and license agreement with Genentech is in place for the identification and development of Bicycle peptides for multiple immuno-oncology targets.

Headline News

Mon, 01 Jun 2026
Bicycle Therapeutics: Trading Below Cash Amid Multiple Uncertainties (NASDAQ:BCYC) - Seeking Alpha

Thu, 21 May 2026
Duravelo-2 bladder cancer data from Bicycle (NASDAQ: BCYC) - Stock Titan

Mon, 20 Apr 2026
[8-K] BICYCLE THERAPEUTICS PLC Reports Material Event - Stock Titan

Fri, 17 Apr 2026
Morgan Stanley Updates Bicycle Therapeutics plc (BCYC) Outlook Amid Pipeline Refocus - Yahoo Finance

Sat, 04 Apr 2026
RBC Capital Lowers its Price Target on Bicycle Therapeutics plc (BCYC) to $7 from $11 - Yahoo Finance

Fri, 13 Mar 2026
Bicycle Therapeutics plc (BCYC) Stock Analysis: A Biotechnology Innovator with 273% Potential Upside - DirectorsTalk Interviews

Financial Analysis
Price to Book Value:
P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly.
Outperform
Price to Earnings:
PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS).
Underperform
Discounted cash flow:
DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows.
Underperform
Return on Assets:
ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit.
Underperform
Return on Equity:
ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency.
Underperform
Debt to Equity:
evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn.
Neutral
Stock Basics & Statistics
Exchange:
NASDAQ
Sector:
Healthcare
Industry:
Biotechnology
Shares Out 0 (M)
Shares Float 50 (M)
Held by Insiders 0 (%)
Held by Institutions 4.4 (%)
Shares Short 2,930 (K)
Shares Short P.Month 0 (K)
Stock Financials
EPS -2.3223e+008
EPS Est Next Qtrly 0
EPS Est This Year 0
EPS Est Next Year 0
Book Value (p.s.) 0
Profit Margin 0 %
Operating Margin -7 %
Return on Assets (ttm) 382.4 %
Return on Equity (ttm) -19.4 %
Qtrly Rev. Growth 6.35e+007 %
Gross Profit (p.s.) -59.16
Sales Per Share -21.98
EBITDA (p.s.) -1.00825e+008
Qtrly Earnings Growth -3.2 %
Operating Cash Flow 0 (M)
Levered Free Cash Flow -229 (M)
Stock Valuations
PE Ratio -0.01
PEG Ratio 0
Price to Book value 0
Price to Sales -0.19
Price to Cash Flow 0.78
Stock Dividends
Dividend 0
Forward Dividend 2.86e+006
Dividend Yield 0%
Dividend Pay Date Invalid DateTime.
Ex-Dividend Date Invalid DateTime.

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