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Checkpoint Therapeutics, Inc. is a clinical-stage company specializing in immunotherapy and targeted oncology. Its mission involves discovering, advancing, and bringing to market innovative therapeutic solutions for individuals battling solid tumor cancers. The company's pipeline features several key candidates, including Cosibelimab, a leading fully-human IgG1 monoclonal antibody. This therapy is designed to directly bind to programmed death ligand-1 (PD-L1), thereby inhibiting its interaction with programmed death receptor-1 and B7.1 receptors. Another significant antibody in development is CK-302, a human agonistic antibody intended to bind and activate signaling within GITR-expressing cells. Beyond antibodies, Checkpoint Therapeutics is advancing Olafertinib, a third-generation epidermal growth factor receptor (EGFR) inhibitor specifically for patients with EGFR mutation-positive non-small cell lung cancer. Its portfolio also includes CK-103, a highly selective and potent small molecule designed to inhibit bromodomain and extra-terminal (BET) bromodomains. Furthermore, a fully human, preclinical anti-carbonic anhydrase IX (CAIX) antibody is being developed, which aims to identify and destroy CAIX-expressing cells through both antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). To broaden its reach, Checkpoint Therapeutics has established collaboration agreements with TG Therapeutics, Inc. These partnerships focus on the joint development and commercialization of specific assets related to its licenses in the area of hematological malignancies. Established in 2014, Checkpoint Therapeutics is headquartered in Waltham, Massachusetts, and operates as a subsidiary of Fortress Biotech, Inc.
Fri, 30 May 2025
Checkpoint Therapeutics finalizes acquisition by Sun Pharma - Investing.com
Mon, 10 Mar 2025
On the heels of FDA nod for cancer drug, Sun Pharma buys Checkpoint Therapeutics for up to $416M - Fierce Pharma
Sun, 09 Mar 2025
Sun Pharma to Acquire Checkpoint Therapeutics - PR Newswire
Fri, 13 Dec 2024
US FDA approves Checkpoint's skin cancer drug - Reuters
Fri, 13 Dec 2024
Checkpoint Therapeutics Announces FDA Approval of UNLOXCYT™ (cosibelimab-ipdl) - GlobeNewswire
Mon, 16 Sep 2024
H.C. Wainwright Maintains Checkpoint Therapeutics(CKPT.US) With Buy Rating, Maintains Target Price $20 - Moomoo
| Price to Book Value: P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly. |
Underperform |
| Price to Earnings: PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS). |
Underperform |
| Discounted cash flow: DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows. |
Neutral |
| Return on Assets: ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit. |
Underperform |
| Return on Equity: ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency. |
Underperform |
| Debt to Equity: evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn. |
Underperform |
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Exchange:
NASDAQ
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Sector:
Healthcare
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Industry:
Biotechnology
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