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Global Blood Therapeutics, Inc. (GBT) is a biopharmaceutical firm dedicated to discovering, developing, and providing therapies for patients suffering from sickle cell disease (SCD) who currently lack adequate treatment options. Its marketed product, Oxbryta tablets, offers a once-daily, oral treatment for SCD. Furthermore, GBT is conducting a Phase IIa clinical trial to assess the safety and pharmacokinetic profile of single and multiple doses of Oxbryta in younger SCD patients, including adolescents and children. In its development pipeline, inclacumab stands as a primary candidate – a novel human monoclonal antibody currently undergoing Phase IIIa clinical trials. This investigational drug aims to diminish the occurrence of painful vaso-occlusive crises and subsequent hospitalizations. Also in early-stage development (Phase I) is GBT601, a compound designed to inhibit hemoglobin polymerization. The company holds a licensing and collaborative agreement with Syros Pharmaceuticals, Inc. focused on identifying, advancing, and commercializing treatments for both SCD and beta thalassemia. Additionally, GBT collaborates with Sanofi S.A. on two separate early-stage research initiatives targeting SCD. Established in 2011, Global Blood Therapeutics, Inc. maintains its headquarters in South San Francisco, California.
Tue, 31 Mar 2026
Pfizer to exit South San Francisco space — and with it, the Bay Area - The Business Journals
Mon, 18 Aug 2025
Pfizer's SCD drug fails phase 3 study in latest blow to Global Blood Therapeutics' legacy - Fierce Biotech
Fri, 18 Apr 2025
Exclusive | Pfizer in Advanced Talks to Buy Global Blood Therapeutics for About $5 Billion - WSJ
Mon, 05 Feb 2024
How Dr. Ted Love Sold His Sickle Cell Company To Pfizer For $5.4 Billion - Forbes
Tue, 11 Oct 2022
Pfizer Fully Acquires Global Blood Therapeutics, Oxbryta for SCD |... - Sickle Cell Disease News
Wed, 05 Oct 2022
Pfizer finalizes acquisition of Global Blood Therapeutics - drugdiscoverytrends.com
| Price to Book Value: P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly. |
Outperform |
| Price to Earnings: PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS). |
Underperform |
| Discounted cash flow: DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows. |
Outperform |
| Return on Assets: ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit. |
Neutral |
| Return on Equity: ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency. |
Underperform |
| Debt to Equity: evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn. |
Outperform |
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Exchange:
NASDAQ
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Sector:
Healthcare
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Industry:
Biotechnology
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