stoxline Quote Chart Rank Option Currency Glossary
  
Ionis Pharmaceuticals, Inc. (IONS)
76.5  -0.83 (-1.07%)    05-29 16:00
Open: 77.285
High: 78.1
Volume: 1,353,450
  
Pre. Close: 77.33
Low: 76.47
Market Cap: 12,643(M)
Technical analysis
2026-05-29 4:44:47 PM
Short term     
Mid term     
Targets 6-month :  92.49 1-year :  108.03
Resists First :  79.19 Second :  92.49
Pivot price 75.57
Supports First :  74.23 Second :  71.18
MAs MA(5) :  76.38 MA(20) :  75.62
MA(100) :  77.38 MA(250) :  66.31
MACD MACD :  0.3 Signal :  0.1
%K %D K(14,3) :  66.5 D(3) :  62.5
RSI RSI(14): 54.5
52-week High :  86.73 Low :  33.43
Price, MAs and Bollinger Bands

Price has closed above its short-term moving average. Short-term moving average is currently above mid-term; and below long-term moving average. From the relationship between price and moving averages: This stock is BULLISH in short-term; and NEUTRAL in mid-long term.
[ IONS ] has closed below upper band by 31.5%. Bollinger Bands are 30.7% narrower than normal. The current width of the bands does not suggest anything about the future direction or movement of prices.

Stock Price Prediction
If tomorrow: Open lower Open higher
High: 78.14 - 78.54 78.54 - 78.85
Low: 75.54 - 75.96 75.96 - 76.28
Close: 75.84 - 76.54 76.54 - 77.07
Company Description

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an injection for the treatment of polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; and WAYLIVRA, a treatment for familial chylomicronemia syndrome and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of TTR amyloidosis; Olezarsen for patients with severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Tofersen to inhibit the production of superoxide dismutase 1. In addition, the company develops medicines for metabolic diseases, infectious diseases, renal diseases, ophthalmic diseases, and cancer. It has a strategic collaboration with Biogen Inc.; and collaboration and license agreement with AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis AG, Roche, Janssen Biotech, Inc., and Flamingo Therapeutics, Inc. Ionis Pharmaceuticals, Inc. was founded in 1989 and is based in Carlsbad, California.

Headline News

Fri, 29 May 2026
Why Is Ionis Pharmaceuticals (IONS) Up 3.4% Since Last Earnings Report? - Yahoo Finance

Fri, 29 May 2026
GSK, Ionis mark late-stage trial win for chronic hepatitis B therapy - MSN

Thu, 28 May 2026
Ionis Pharmaceuticals: Bull Run Can Continue As Major Catalysts Approach (NASDAQ:IONS) - Seeking Alpha

Thu, 28 May 2026
Ionis partner GSK announces bepirovirsen achieves unprecedented functional cure rates with potential to redefine treatment for chronic hepatitis B - Business Wire

Thu, 28 May 2026
New hepatitis B drug shows 19% functional cure in late-stage trials - Stock Titan

Tue, 26 May 2026
Ionis Pharmaceuticals Inc (MIL:1IONS) Stock Price, Trades & News - GuruFocus

Financial Analysis
Price to Book Value:
P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly.
Underperform
Price to Earnings:
PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS).
Underperform
Discounted cash flow:
DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows.
Underperform
Return on Assets:
ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit.
Underperform
Return on Equity:
ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency.
Underperform
Debt to Equity:
evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn.
Underperform
Stock Basics & Statistics
Exchange:
NASDAQ
Sector:
Healthcare
Industry:
Biotechnology
Shares Out 165 (M)
Shares Float 164 (M)
Held by Insiders 0.6 (%)
Held by Institutions 107.6 (%)
Shares Short 16,280 (K)
Shares Short P.Month 14,330 (K)
Stock Financials
EPS -2.01
EPS Est Next Qtrly 0
EPS Est This Year 0
EPS Est Next Year 0
Book Value (p.s.) 2.96
Profit Margin -30.9 %
Operating Margin -47.8 %
Return on Assets (ttm) -7.1 %
Return on Equity (ttm) -67.7 %
Qtrly Rev. Growth 87 %
Gross Profit (p.s.) 0.7
Sales Per Share 6.41
EBITDA (p.s.) -2.05
Qtrly Earnings Growth 0 %
Operating Cash Flow -911 (M)
Levered Free Cash Flow -808 (M)
Stock Valuations
PE Ratio -38.06
PEG Ratio 27.3
Price to Book value 25.84
Price to Sales 11.92
Price to Cash Flow -13.89
Stock Dividends
Dividend 0
Forward Dividend 0
Dividend Yield 0%
Dividend Pay Date Invalid DateTime.
Ex-Dividend Date Invalid DateTime.

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