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IVERIC bio, Inc. is a biopharmaceutical enterprise focused on identifying and advancing innovative therapeutic solutions for eye conditions, with a particular emphasis on age-related and rare inherited retinal diseases (IRDs). A cornerstone of its development pipeline is Zimura, an inhibitor targeting complement factor C5. This compound is currently undergoing investigation for geographic atrophy (GA), a severe form of dry age-related macular degeneration (AMD). Zimura's clinical progression includes the GATHER1 trial, which has successfully concluded its Phase 2/3 stage, and the GATHER2 trial, which is presently in Phase 3. The company's portfolio also features STAR (identified as OPH2005), a candidate in Phase 2b clinical trials for addressing Leber congenital amaurosis type 10 (LCA10) and autosomal recessive Stargardt disease (STGD1). Additionally, IVERIC bio is developing IC-500, a high-temperature requirement A serine peptidase 1 protein inhibitor intended for GA and other forms of age-related retinal degeneration. Other programs include IC-100, aimed at rhodopsin-mediated autosomal dominant retinitis pigmentosa, and IC-200, designed for IRDs stemming from mutations in the BEST1 gene. Beyond these active programs, the company has completed several earlier clinical trials: OPH2001, a Phase 1/2a study evaluating various doses of Zimura monotherapy for GA; OPH2000, a Phase 1/2a trial assessing different doses of Zimura combined with Lucentis for wet AMD; OPH2007, which concluded its Phase 2a study for wet AMD; and OPH2002, a Phase 2a trial for idiopathic polypoidal choroidal vasculopathy. In its earlier-stage research and discovery efforts, IVERIC bio is exploring programs such as miniCEP290 for LCA10, miniABCA4 for STGD1, and miniUSH2A for Usher syndrome type 2A-related IRDs. Established in 2007, the company, originally known as Ophthotech Corporation, adopted its current name, IVERIC bio, Inc., in April 2019. Its operations are based in Parsippany, New Jersey.
Sun, 30 Aug 2026
IVERIC bio Inc. (ISEE) Peer Comparison – Compare with Others - Value Research
Sun, 30 Aug 2026
IVERIC bio Inc. (ISEE) Shareholding Pattern – Promoters, FIIs & DIIs - Value Research
Wed, 05 Jul 2023
Iveric Bio Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - Business Wire
Sun, 30 Apr 2023
Astellas Enters into Definitive Agreement to Acquire Iveric Bio - PR Newswire
Sun, 23 Apr 2023
Iveric Bio Announces New Functional Vision Loss Reduction Data from Avacincaptad Pegol GATHER Trials Presented at ARVO Annual Meeting - BioSpace
| Price to Book Value: P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly. |
Outperform |
| Price to Earnings: PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS). |
Underperform |
| Discounted cash flow: DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows. |
Outperform |
| Return on Assets: ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit. |
Underperform |
| Return on Equity: ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency. |
Underperform |
| Debt to Equity: evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn. |
Neutral |
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Exchange:
NASDAQ
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Sector:
Healthcare
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Industry:
Biotechnology
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