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Karyopharm Therapeutics Inc. (KPTI)
9.5  0.5 (5.56%)    06-12 16:00
Open: 9.1
High: 10.21
Volume: 564,583
  
Pre. Close: 9
Low: 9.04
Market Cap: 215(M)
Technical analysis
2026-06-12 4:45:34 PM
Short term     
Mid term     
Targets 6-month :  11.94 1-year :  13.95
Resists First :  10.22 Second :  11.94
Pivot price 9.02
Supports First :  8.14 Second :  6.84
MAs MA(5) :  8.96 MA(20) :  8.68
MA(100) :  8.09 MA(250) :  6.71
MACD MACD :  0.1 Signal :  0.1
%K %D K(14,3) :  63.7 D(3) :  61.2
RSI RSI(14): 58.8
52-week High :  10.98 Low :  3.65
Price, MAs and Bollinger Bands

Price has closed above its short-term moving average. Short-term moving average is currently above mid-term; and above long-term moving average. From the relationship between price and moving averages: This stock is BULLISH in short-term; and BULLISH in mid-long term.
[ KPTI ] has closed below upper band by 17.8%. Bollinger Bands are 51.6% narrower than normal. The narrow width of the bands suggests low volatility as compared to its normal range. The bands have been in this narrow range for 1 bars. This is a sign that the market may be about to initiate a new trend.

Stock Price Prediction
If tomorrow: Open lower Open higher
High: 10.22 - 10.27 10.27 - 10.31
Low: 8.93 - 8.98 8.98 - 9.03
Close: 9.41 - 9.5 9.5 - 9.57
Company Description

Karyopharm Therapeutics Inc. is a pharmaceutical company that has already brought products to market, focusing on identifying, advancing, and selling medications designed to disrupt nuclear export pathways. These drugs are primarily aimed at treating cancer and various other illnesses. The company's strategy involves researching, creating, and marketing innovative Selective Inhibitor of Nuclear Export (SINE) compounds, which operate by attaching to and deactivating the nuclear export protein XPO1. Their leading therapeutic, XPOVIO, holds approvals for several critical applications in adult patients: it is prescribed in combination with bortezomib and dexamethasone for multiple myeloma; alongside dexamethasone for those with heavily pretreated multiple myeloma; and as a standalone treatment for relapsed or refractory diffuse large B-cell lymphoma. Karyopharm has also established a licensing partnership with the Menarini Group, granting them rights to develop and market NEXPOVIO for human oncology indications across Europe (including the United Kingdom), Latin America, and other global regions. Furthermore, the company's oral SINE compounds are specifically engineered to promote the accumulation of various tumor suppressor and growth-regulating proteins within the cell nucleus. Established in 2008, Karyopharm Therapeutics Inc. maintains its principal offices in Newton, Massachusetts.

Headline News

Wed, 03 Jun 2026
Karyopharm to Participate in Webcast Featuring Endometrial Cancer Key Opinion Leader on June 8, 2026 - Karyopharm

Mon, 01 Jun 2026
Karyopharm Therapeutics Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) - PR Newswire

Wed, 27 May 2026
Wall Street Analysts Think Karyopharm Therapeutics (KPTI) Could Surge 70.46%: Read This Before Placing a Bet - Yahoo Finance

Thu, 07 May 2026
Karyopharm to Report First Quarter 2026 Financial Results on May 14, 2026 - Karyopharm

Tue, 21 Apr 2026
Karyopharm's Phase 3 SENTRY Trial in Myelofibrosis Selected for Late-Breaking Oral Presentation at ASCO 2026 Annual Meeting - PR Newswire

Fri, 17 Apr 2026
RBC Flags Seasonal Pressures Impacting Karyopharm Therapeutics Inc. (KPTI) Short-Term Performance - Yahoo Finance

Financial Analysis
Price to Book Value:
P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly.
Underperform
Price to Earnings:
PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS).
Underperform
Discounted cash flow:
DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows.
Neutral
Return on Assets:
ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit.
Underperform
Return on Equity:
ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency.
Outperform
Debt to Equity:
evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn.
Underperform
Stock Basics & Statistics
Exchange:
NASDAQ
Sector:
Healthcare
Industry:
Biotechnology
Shares Out 23 (M)
Shares Float 15 (M)
Held by Insiders 4.6 (%)
Held by Institutions 83.4 (%)
Shares Short 5,280 (K)
Shares Short P.Month 5,720 (K)
Stock Financials
EPS -16.4
EPS Est Next Qtrly 0
EPS Est This Year 0
EPS Est Next Year 0
Book Value (p.s.) -16
Profit Margin -129.1 %
Operating Margin -76.4 %
Return on Assets (ttm) -40.7 %
Return on Equity (ttm) 0 %
Qtrly Rev. Growth 16.7 %
Gross Profit (p.s.) 0.89
Sales Per Share 6.66
EBITDA (p.s.) -3.71
Qtrly Earnings Growth 0 %
Operating Cash Flow 0 (M)
Levered Free Cash Flow 0 (M)
Stock Valuations
PE Ratio -0.58
PEG Ratio 0
Price to Book value -0.6
Price to Sales 1.42
Price to Cash Flow 0
Stock Dividends
Dividend 0
Forward Dividend 0
Dividend Yield 0%
Dividend Pay Date Invalid DateTime.
Ex-Dividend Date Invalid DateTime.

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