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Karyopharm Therapeutics Inc. (KPTI)
8.45  0.17 (2.05%)    04-14 16:00
Open: 8.4
High: 8.57
Volume: 559,865
  
Pre. Close: 8.28
Low: 8.3
Market Cap: 72(M)
Technical analysis
2026-04-14 3:45:30 PM
Short term     
Mid term     
Targets 6-month :  10.55 1-year :  12.33
Resists First :  9.03 Second :  10.55
Pivot price 6.52
Supports First :  6.54 Second :  5
MAs MA(5) :  8.01 MA(20) :  6.83
MA(100) :  7.21 MA(250) :  6.12
MACD MACD :  0 Signal :  -0.3
%K %D K(14,3) :  82.2 D(3) :  76.9
RSI RSI(14): 61.6
52-week High :  10.98 Low :  3.65
Price, MAs and Bollinger Bands

Price has closed above its short-term moving average. Short-term moving average is currently above mid-term; and above long-term moving average. From the relationship between price and moving averages: This stock is BULLISH in short-term; and BULLISH in mid-long term.
[ KPTI ] has closed below upper band by 10.1%. Bollinger Bands are 74.1% wider than normal. The large width of the bands suggest high volatility as compared to its normal range. The bands have been in this wide range for 14 days. This is a sign that the current trend might continue.

Stock Price Prediction
If tomorrow: Open lower Open higher
High: 8.88 - 8.92 8.92 - 8.95
Low: 7.95 - 7.99 7.99 - 8.02
Close: 8.21 - 8.28 8.28 - 8.33
Company Description

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases. The company discovers, develops, and commercializes novel and Selective Inhibitor of Nuclear Export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1. Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma, and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. The company has license agreement with Menarini Group to develop and commercialize NEXPOVIO for human oncology indications in Europe, including the United Kingdom; Latin America; and other countries. Its oral SINE compounds also designed to force nuclear accumulation in the levels of multiple tumor suppressor and growth regulatory proteins. The company was incorporated in 2008 and is headquartered in Newton, Massachusetts.

Headline News

Mon, 13 Apr 2026
Karyopharm Therapeutics (KPTI) affiliated managers report 1.9%–2.3% stakes - Stock Titan

Mon, 13 Apr 2026
Karyopharm (KPTI) seeks approval for director slate and larger equity plans - Stock Titan

Sat, 11 Apr 2026
Karyopharm to seek label expansion for Xpovio in myelofibrosis after late-stage trial win - MSN

Fri, 27 Mar 2026
Karyopharm Therapeutics (KPTI) Stock Jumps 6.9%: Will It Continue to Soar? - Yahoo Finance

Fri, 27 Mar 2026
Karyopharm Therapeutics (KPTI) Stock Jumps 6.9%: Will It Continue to Soar? - qz.com

Wed, 25 Mar 2026
Karyopharm Therapeutics Inc. (KPTI) Discusses Top Line Results From Phase III SENTRY Trial in Myelofibrosis - Slideshow (NASDAQ:KPTI) 2026-03-25 - Seeking Alpha

Financial Analysis
Price to Book Value:
P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly.
Underperform
Price to Earnings:
PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS).
Underperform
Discounted cash flow:
DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows.
Neutral
Return on Assets:
ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit.
Underperform
Return on Equity:
ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency.
Outperform
Debt to Equity:
evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn.
Underperform
Stock Basics & Statistics
Exchange:
NASDAQ
Sector:
Healthcare
Industry:
Biotechnology
Shares Out 23 (M)
Shares Float 17 (M)
Held by Insiders 5.5 (%)
Held by Institutions 49.5 (%)
Shares Short 3,590 (K)
Shares Short P.Month 2,470 (K)
Stock Financials
EPS -17.94
EPS Est Next Qtrly 0
EPS Est This Year 0
EPS Est Next Year 0
Book Value (p.s.) -16
Profit Margin -134.3 %
Operating Margin -52.4 %
Return on Assets (ttm) -41.6 %
Return on Equity (ttm) 0 %
Qtrly Rev. Growth 11.6 %
Gross Profit (p.s.) 0.64
Sales Per Share 6.48
EBITDA (p.s.) -4.02
Qtrly Earnings Growth 0 %
Operating Cash Flow -75 (M)
Levered Free Cash Flow -49 (M)
Stock Valuations
PE Ratio -0.47
PEG Ratio 0
Price to Book value -0.53
Price to Sales 1.29
Price to Cash Flow -2.52
Stock Dividends
Dividend 0
Forward Dividend 0
Dividend Yield 0%
Dividend Pay Date Invalid DateTime.
Ex-Dividend Date Invalid DateTime.

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