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Oncternal Therapeutics, Inc. is a clinical-stage biopharmaceutical firm dedicated to creating cancer treatments for diseases where current medical options are insufficient. Its clinical-stage portfolio features zilovertamab, a humanized monoclonal antibody designed to bind to ROR1 (Receptor-tyrosine kinase-like Orphan Receptor 1), and ONCT-216, a small molecule that works by inhibiting the biological activity of ETS-family transcription factor oncoproteins. Additionally, Oncternal is advancing ONCT-808, a chimeric antigen receptor T-cell (CAR-T) therapy candidate also targeting ROR1, as well as ONCT-534, a dual-action androgen receptor inhibitor aimed at treating castration-resistant prostate cancer and other cancers driven by androgen receptors. The company holds various license agreements with institutions such as the Regents of the University of California, Georgetown University, The University of Texas MD Anderson Cancer Center, Shanghai Pharmaceutical (USA) Inc., and the University of Tennessee Research Foundation. Furthermore, it engages in a research collaboration with Celularity Inc. to explore placental-derived cellular therapies that also target ROR1. Its headquarters are located in San Diego, California.
Tue, 01 Jul 2025
ROR deal: Oncternal sells cancer assets to mystery biotech for $3M, winds down operations - Fierce Biotech
Tue, 01 Jul 2025
Oncternal sells assets for up to $68m and calls it quits - Pharmaceutical Technology
Thu, 24 Apr 2025
Oncternal Therapeutics (ONCT) Stock Price, News & Analysis - Stock Titan
Thu, 07 Nov 2024
Phase 1/2 trial of ONCT-534 in mCRPC has been terminated - Urology Times
Thu, 12 Sep 2024
Oncternal folds all clinical trials after lackluster data drop, patient death - Fierce Biotech
Thu, 04 Jan 2024
Oncternal Therapeutics Announces Reverse Stock Split - Stock Titan
| Price to Book Value: P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly. |
Outperform |
| Price to Earnings: PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS). |
Underperform |
| Discounted cash flow: DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows. |
Neutral |
| Return on Assets: ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit. |
Underperform |
| Return on Equity: ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency. |
Underperform |
| Debt to Equity: evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn. |
Underperform |
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Exchange:
NASDAQ
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Sector:
Healthcare
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Industry:
Biotechnology
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