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Sage Therapeutics, Inc. functions as a biopharmaceutical enterprise, dedicated to the discovery, development, and market introduction of therapeutic agents aimed at central nervous system (CNS) conditions. Its primary medication is ZULRESSO, an intravenous form of brexanolone, prescribed for the treatment of postpartum depression (PPD) in adult patients. The company's advanced pipeline includes zuranolone, a neuroactive steroid, which is presently undergoing Phase III clinical trials for several disorders, such as PPD, major depressive disorders, treatment-resistant depression, generalized anxiety disorders, and bipolar depression. Another investigational compound, SAGE-324, is in Phase II studies for essential tremors, having already completed Phase I trials for epilepsy and Parkinson's disease. Furthermore, SAGE-718, an oxysterol-based positive allosteric modulator of the NMDA receptor, has concluded its Phase I clinical assessments for a range of indications including depression, Huntington's disease, Alzheimer's disease, attention deficit hyperactivity disorder, schizophrenia, and neuropathic pain. To enhance its global reach and innovative efforts, Sage Therapeutics has established significant collaborations. This comprises a strategic partnership with Shionogi & Co., Ltd. for the advancement and commercialization of zuranolone in Japan, Taiwan, and South Korea. Additionally, the company holds a collaboration and licensing agreement with Biogen MA Inc. for the joint development and marketing of its SAGE-217 and SAGE-324 products. Incorporated in 2010 and based in Cambridge, Massachusetts, the firm was initially known as Sterogen Biopharma, Inc., before officially changing its name to Sage Therapeutics, Inc. in September 2011.
Thu, 11 Jun 2026
Ex‑Sage drug chief joins effort on potential Prader‑Willi therapy - Stock Titan
Sun, 17 May 2026
Sage Therapeutics stock (US78433J1043): focus shifts to zuranolone strategy after latest updates - AD HOC NEWS
Tue, 21 Apr 2026
Former Sage Therapeutics executives launch neurology biotech with $106M - The Business Journals
Tue, 02 Sep 2025
Sage Therapeutics, Inc. (SAGE) Bought by Supernus to Boost Neuropsychiatric Portfolio - Yahoo Finance
Thu, 31 Jul 2025
Supernus Pharmaceuticals Completes Acquisition of Sage Therapeutics - Quiver Quantitative
Wed, 30 Jul 2025
Saphire, Inc completed the acquisition of Sage Therapeutics, Inc.. - marketscreener.com
| Price to Book Value: P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly. |
Outperform |
| Price to Earnings: PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS). |
Underperform |
| Discounted cash flow: DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows. |
Underperform |
| Return on Assets: ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit. |
Underperform |
| Return on Equity: ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency. |
Underperform |
| Debt to Equity: evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn. |
Neutral |
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Exchange:
NASDAQ
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Sector:
Healthcare
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Industry:
Biotechnology
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