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Silence Therapeutics plc (SLN)
9.16  1.89 (26%)    06-24 16:00
Open: 7.59
High: 9.46
Volume: 2,225,651
  
Pre. Close: 7.27
Low: 7.43
Market Cap: 433(M)
Technical analysis
2026-06-24 4:47:01 PM
Short term     
Mid term     
Targets 6-month :  11.04 1-year :  12.9
Resists First :  9.46 Second :  11.04
Pivot price 6.82
Supports First :  7.16 Second :  5.73
MAs MA(5) :  7.53 MA(20) :  6.79
MA(100) :  6.24 MA(250) :  6.04
MACD MACD :  0.2 Signal :  0
%K %D K(14,3) :  80.7 D(3) :  77.2
RSI RSI(14): 72.4
52-week High :  9.46 Low :  4.19
Price, MAs and Bollinger Bands

Price has closed above its short-term moving average. Short-term moving average is currently above mid-term; and above long-term moving average. From the relationship between price and moving averages: This stock is BULLISH in short-term; and BULLISH in mid-long term.
[ SLN ] has closed It is unclear right now based on current values. 55.3% wider than normal. The large width of the bands suggest high volatility as compared to its normal range. The bands have been in this wide range for 0 days. This is a sign that the current trend might continue.

Stock Price Prediction
If tomorrow: Open lower Open higher
High: 9.47 - 9.51 9.51 - 9.54
Low: 7.35 - 7.38 7.38 - 7.42
Close: 9.08 - 9.16 9.16 - 9.22
Company Description

Silence Therapeutics plc is a London, UK-based biotechnology company specializing in the research and development of groundbreaking ribonucleic acid (RNA) therapeutics. Its therapeutic focus areas include hematological, cardiovascular, and various rare and metabolic conditions. Central to their innovative approach is the mRNAi GalNAc Oligonucleotide Discovery platform, which is designed for precise targeting of specific disease-causing genes within the liver. The company's methodology harnesses the body's natural RNA interference (RNAi) mechanism by designing short interfering RNA (siRNA) molecules that degrade messenger RNA (mRNA), thereby preventing the production of targeted disease-associated proteins. Their pipeline features several promising candidates, including SLN360, currently in Phase I clinical trials for cardiovascular disease associated with elevated lipoprotein. Another key candidate, SLN124, is undergoing Phase I clinical trials for non-transfusion-dependent thalassemia and myelodysplastic syndrome, with further development planned for polycythemia vera. Silence Therapeutics also engages in strategic collaborations to expand its reach. It has agreements with AstraZeneca PLC to discover, develop, and commercialize siRNA therapeutics for cardiovascular, renal, metabolic, and respiratory diseases. Furthermore, a partnership with Mallinckrodt Pharma IP Trading DAC aims to develop and commercialize RNAi drug targets designed to silence the complement cascade in complement-mediated disorders. The company is also collaborating with Hansoh Pharmaceutical Group Company Limited to develop siRNAs for three unspecified targets, utilizing Silence's mRNAi GOLD platform. Originally incorporated as SR Pharma plc, the company rebranded to Silence Therapeutics plc in May 2007.

Headline News

Wed, 24 Jun 2026
Why Is Silence Therapeutics Stock Soaring Wednesday? - Silence Therapeutics (NASDAQ:SLN) - Benzinga

Wed, 24 Jun 2026
Why is Silence Therapeutics stock surging today? - Investing.com

Wed, 24 Jun 2026
Silence Therapeutics stock jumps on Cantor Fitzgerald upgrade - Investing.com

Tue, 23 Jun 2026
Silence Therapeutics updates corporate presentation highlighting Divesiran Phase 2 topline timing and pipeline progress - TradingView

Tue, 23 Jun 2026
Silence Therapeutics (NASDAQ: SLN) details divesiran, SLN312 and obesity siRNA plans - Stock Titan

Wed, 17 Jun 2026
How Silence Therapeutics (SLN) Is Building the Divesiran Case Around Fewer Blood Draws in Polycythemia Vera - Yahoo Finance

Financial Analysis
Price to Book Value:
P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly.
Underperform
Price to Earnings:
PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS).
Underperform
Discounted cash flow:
DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows.
Neutral
Return on Assets:
ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit.
Underperform
Return on Equity:
ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency.
Underperform
Debt to Equity:
evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn.
Outperform
Stock Basics & Statistics
Exchange:
NASDAQ
Sector:
Healthcare
Industry:
Biotechnology
Shares Out 0 (M)
Shares Float 47 (M)
Held by Insiders 2.492e+007 (%)
Held by Institutions 24.3 (%)
Shares Short 2,160 (K)
Shares Short P.Month 0 (K)
Stock Financials
EPS -7.108e+007
EPS Est Next Qtrly 0
EPS Est This Year 0
EPS Est Next Year 0
Book Value (p.s.) 0
Profit Margin 0 %
Operating Margin -3 %
Return on Assets (ttm) 565.4 %
Return on Equity (ttm) -29.8 %
Qtrly Rev. Growth 839000 %
Gross Profit (p.s.) -75.12
Sales Per Share -67.88
EBITDA (p.s.) 258647
Qtrly Earnings Growth -1.7 %
Operating Cash Flow 0 (M)
Levered Free Cash Flow -66 (M)
Stock Valuations
PE Ratio -0.01
PEG Ratio 0
Price to Book value 0
Price to Sales -0.14
Price to Cash Flow 0
Stock Dividends
Dividend 0
Forward Dividend 2.06e+006
Dividend Yield 0%
Dividend Pay Date Invalid DateTime.
Ex-Dividend Date Invalid DateTime.

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