stoxline Quote Chart Rank Option Currency Glossary
  
Silence Therapeutics plc (SLN)
5  -0.2 (-3.85%)    10-03 16:00
Open: 5.19
High: 5.26
Volume: 75,562
  
Pre. Close: 5.2
Low: 4.9
Market Cap: 236(M)
Technical analysis
2025-10-04 3:49:33 PM
Short term     
Mid term     
Targets 6-month :  6.17 1-year :  6.8
Resists First :  5.28 Second :  5.82
Pivot price 5.1
Supports First :  4.42 Second :  3.67
MAs MA(5) :  5.23 MA(20) :  5.06
MA(100) :  5.45 MA(250) :  6.74
MACD MACD :  -0.1 Signal :  -0.1
%K %D K(14,3) :  48.3 D(3) :  55.1
RSI RSI(14): 46.5
52-week High :  20.47 Low :  1.97
Price, MAs and Bollinger Bands

Price has closed below its short-term moving average. Short-term moving average is currently below mid-term; and below long-term moving average. From the relationship between price and moving averages: This stock is BEARISH in short-term; and BEARISH in mid-long term.
[ SLN ] has closed above bottom band by 39.0%. Bollinger Bands are 25.2% narrower than normal. The current width of the bands does not suggest anything about the future direction or movement of prices.

Stock Price Prediction
If tomorrow: Open lower Open higher
High: 5.27 - 5.29 5.29 - 5.32
Low: 4.83 - 4.86 4.86 - 4.89
Close: 4.94 - 4.99 4.99 - 5.04
Company Description

Silence Therapeutics plc, a biotechnology company, focuses on the discovery and development of novel ribonucleic acid (RNA) therapeutics in hematology, cardiovascular, and other rare and metabolic indications. The company's platform includes mRNAi GalNAc Oligonucleotide Discovery platform designed to accurately target specific disease-associated genes in the liver. It designs short interfering RNA molecules to harness the body's natural mechanism of RNA interference, and degrading messenger RNA molecules that encode specific targeted disease-associated proteins in a cell. The company is developing various product candidates, including SLN360, which is Phase I clinical trials for the treatment of cardiovascular disease with high lipoprotein; SLN124 that is in Phase I clinical trials for the treatment of non-transfusion dependent thalassemia, and Phase I clinical trials for the treatment of myelodysplastic syndrome; and SLN124 for the treatment of polycythemia vera. It has collaboration agreements with AstraZeneca PLC to discover, develop, and commercialize small interfering RNA therapeutics for the treatment of cardiovascular, renal, metabolic, and respiratory diseases; and Mallinckrodt Pharma IP Trading DAC to develop and commercialize RNAi drug targets designed to silence the complement cascade in complement-mediated disorders. The company also has a collaboration with Hansoh Pharmaceutical Group Company Limited to develop siRNAs for three undisclosed targets leveraging Silence's mRNAi GOLD platform. The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc is headquartered in London, the United Kingdom.

Headline News

Sun, 28 Sep 2025
Pinning Down Silence Therapeutics plc's (NASDAQ:SLN) P/S Is Difficult Right Now - simplywall.st

Sun, 28 Sep 2025
Pinning Down Silence Therapeutics plc's (NASDAQ:SLN) P/S Is Difficult Right Now - Sahm

Tue, 02 Sep 2025
Silence Therapeutics to Participate in September Investor Conferences - FinancialContent

Tue, 02 Sep 2025
Silence Therapeutics to Participate in September Investor Conferences - Business Wire

Thu, 07 Aug 2025
Silence Therapeutics Reports Second Quarter 2025 Financial Results and Recent Business Highlights - Business Wire

Thu, 17 Jul 2025
What Silence Therapeutics Plc's (NASDAQ:SLN) 25% Share Price Gain Is Not Telling You - 富途牛牛

Financial Analysis
Price to Book Value:
P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly.
Neutral
Price to Earnings:
PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS).
Underperform
Discounted cash flow:
DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows.
Underperform
Return on Assets:
ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit.
Underperform
Return on Equity:
ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency.
Underperform
Debt to Equity:
evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn.
Underperform
Stock Basics & Statistics
Exchange:
NASDAQ
Sector:
Healthcare
Industry:
Biotechnology
Shares Out 0 (M)
Shares Float 47 (M)
Held by Insiders 7.475e+007 (%)
Held by Institutions 24.3 (%)
Shares Short 770 (K)
Shares Short P.Month 0 (K)
Stock Financials
EPS -7.126e+007
EPS Est Next Qtrly 0
EPS Est This Year 0
EPS Est Next Year 0
Book Value (p.s.) 0
Profit Margin -291.3 %
Operating Margin -9 %
Return on Assets (ttm) 48.2 %
Return on Equity (ttm) -22.3 %
Qtrly Rev. Growth 2.717e+007 %
Gross Profit (p.s.) -51.02
Sales Per Share -48.53
EBITDA (p.s.) 1.5471e+007
Qtrly Earnings Growth -1.7 %
Operating Cash Flow 0 (M)
Levered Free Cash Flow -87 (M)
Stock Valuations
PE Ratio -0.01
PEG Ratio 0
Price to Book value 0
Price to Sales -0.11
Price to Cash Flow 3.46
Stock Dividends
Dividend 0
Forward Dividend 808620
Dividend Yield 0%
Dividend Pay Date Invalid DateTime.
Ex-Dividend Date Invalid DateTime.

StockChart iOS

StoxlineLite iOS

StoxlineLite iOS

OptionCalc iOS

StockChart Android

StoxlineLite Android

StoxlinePro Android

OptionCalc Android