stoxline Quote Chart Rank Option Currency Glossary
  
Spruce Biosciences, Inc. (SPRB)
81.68  1.69 (2.11%)    12-08 16:00
Open: 82.783
High: 82.98
Volume: 90,380
  
Pre. Close: 79.99
Low: 78.6
Market Cap: 47(M)
Technical analysis
2025-12-08 4:51:48 PM
Short term     
Mid term     
Targets 6-month :  126.13 1-year :  150.67
Resists First :  107.99 Second :  129
Pivot price 98.57
Supports First :  74.01 Second :  61.57
MAs MA(5) :  86.29 MA(20) :  101.39
MA(100) :  136.66 MA(250) :  0
MACD MACD :  -7.3 Signal :  -4.5
%K %D K(14,3) :  18.6 D(3) :  24
RSI RSI(14): 38.5
52-week High :  2508.75 Low :  7
Price, MAs and Bollinger Bands

Price has closed below its short-term moving average. Short-term moving average is currently below mid-term; and below long-term moving average. From the relationship between price and moving averages: This stock is BEARISH in short-term; and BEARISH in mid-long term.
[ SPRB ] has closed above bottom band by 12.7%. Bollinger Bands are 81.1% narrower than normal. The narrow width of the bands suggests low volatility as compared to its normal range. The bands have been in this narrow range for 30 bars. This is a sign that the market may be about to initiate a new trend.

Stock Price Prediction
If tomorrow: Open lower Open higher
High: 83.09 - 83.42 83.42 - 83.71
Low: 77.72 - 78.11 78.11 - 78.45
Close: 80.98 - 81.64 81.64 - 82.21
Company Description

Spruce Biosciences, Inc., a biopharmaceutical company, focuses on developing and commercializing novel therapies for rare endocrine disorders. The company engages in developing tildacerfont, a non-steroidal therapy to enhance disease control and reduce steroid burden for adult patients suffering from congenital adrenal hyperplasia (CAH), which is in Phase 2b clinical trial; and to evaluate glucocorticoid reduction and clinical consequences in adult patients with classic CAH that is Phase 2b clinical trial. It is also developing tildacerfont for the treatment of pediatric classic congenital adrenal hyperplasia in children that is in Phase 2 clinical trial; and for females with polycystic ovary syndrome, which is in Phase 2 clinical trial. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize compounds for various pharmaceutical uses. Spruce Biosciences, Inc. was incorporated in 2014 and is headquartered in Daly City, California.

Headline News

Sat, 06 Dec 2025
Wall Street Zen Upgrades Spruce Biosciences (NASDAQ:SPRB) to Hold - MarketBeat

Sat, 06 Dec 2025
Spruce Biosciences (SPRB) Price Target Increased by 55.76% to 213.69 - Nasdaq

Wed, 03 Dec 2025
Leerink Partners Upgrades Spruce Biosciences (SPRB) - Nasdaq

Wed, 03 Dec 2025
SPRB: Leerink Partners Upgrades to Outperform with $160 Target | SPRB Stock News - GuruFocus

Mon, 10 Nov 2025
Spruce Biosciences Reports Third Quarter 2025 Financial Results and Provides Corporate Updates - Business Wire

Wed, 15 Oct 2025
What Makes Spruce Biosciences, Inc. (SPRB) a Strong Momentum Stock: Buy Now? - Yahoo Finance

Financial Analysis
Price to Book Value:
P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly.
Outperform
Price to Earnings:
PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS).
Underperform
Discounted cash flow:
DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows.
Outperform
Return on Assets:
ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit.
Underperform
Return on Equity:
ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency.
Underperform
Debt to Equity:
evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn.
Underperform
Stock Basics & Statistics
Exchange:
NASDAQ
Sector:
Healthcare
Industry:
Biotechnology
Shares Out 0 (M)
Shares Float 1 (M)
Held by Insiders 659500 (%)
Held by Institutions 1.6 (%)
Shares Short 21 (K)
Shares Short P.Month 0 (K)
Stock Financials
EPS -4.946e+007
EPS Est Next Qtrly 0
EPS Est This Year 0
EPS Est Next Year 0
Book Value (p.s.) 0
Profit Margin 0 %
Operating Margin -7 %
Return on Assets (ttm) 100 %
Return on Equity (ttm) -77 %
Qtrly Rev. Growth 697000 %
Gross Profit (p.s.) 0
Sales Per Share -48.12
EBITDA (p.s.) -1.03668e+007
Qtrly Earnings Growth -84.4 %
Operating Cash Flow 0 (M)
Levered Free Cash Flow -48 (M)
Stock Valuations
PE Ratio -0.01
PEG Ratio 0
Price to Book value 0
Price to Sales -1.7
Price to Cash Flow 29.81
Stock Dividends
Dividend 0
Forward Dividend 86920
Dividend Yield 0%
Dividend Pay Date Invalid DateTime.
Ex-Dividend Date Invalid DateTime.

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