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Spruce Biosciences, Inc. (SPRB)
51.89  2.785 (5.67%)    06-12 16:00
Open: 49.91
High: 53.25
Volume: 80,927
  
Pre. Close: 49.105
Low: 49.02
Market Cap: 71(M)
Technical analysis
2026-06-12 4:47:41 PM
Short term     
Mid term     
Targets 6-month :  63.47 1-year :  69.14
Resists First :  54.34 Second :  59.2
Pivot price 50.13
Supports First :  46.5 Second :  38.68
MAs MA(5) :  49.29 MA(20) :  50.48
MA(100) :  61.57 MA(250) :  126.66
MACD MACD :  -1.9 Signal :  -2.2
%K %D K(14,3) :  31.8 D(3) :  23.2
RSI RSI(14): 49.2
52-week High :  838.12 Low :  7
Price, MAs and Bollinger Bands

Price has closed above its short-term moving average. Short-term moving average is currently below mid-term; and below long-term moving average. From the relationship between price and moving averages: This stock is NEUTRAL in short-term; and BEARISH in mid-long term.
[ SPRB ] has closed below upper band by 20.3%. Bollinger Bands are 68.5% narrower than normal. The narrow width of the bands suggests low volatility as compared to its normal range. The bands have been in this narrow range for 6 bars. This is a sign that the market may be about to initiate a new trend.

Stock Price Prediction
If tomorrow: Open lower Open higher
High: 53.34 - 53.6 53.6 - 53.83
Low: 48.42 - 48.71 48.71 - 48.96
Close: 51.41 - 51.89 51.89 - 52.33
Company Description

Spruce Biosciences, Inc., founded in 2014 and situated in Daly City, California, operates as a biopharmaceutical enterprise. Its primary objective is to advance and bring to market innovative treatments, particularly for uncommon endocrine conditions. A central component of its therapeutic pipeline is tildacerfont, a non-steroidal drug candidate. This compound is currently undergoing Phase 2b clinical assessments in adult patients with congenital adrenal hyperplasia (CAH), with the aim of optimizing disease management and lessening dependence on steroid medications by examining reductions in glucocorticoid levels and their clinical consequences. Tildacerfont is also progressing through Phase 2 trials for pediatric classic CAH, as well as investigating its efficacy in women suffering from polycystic ovary syndrome (PCOS). Additionally, Spruce Biosciences maintains a collaborative licensing agreement with Eli Lilly and Company to jointly explore, formulate, and commercialize various pharmaceutical substances.

Headline News

Tue, 09 Jun 2026
Jones Trading initiates Spruce Biosciences stock with buy rating on therapy potential By Investing.com - Investing.com Australia

Mon, 08 Jun 2026
Spruce Biosciences (SPRB) Reports Promising Long-Term Results fo - GuruFocus

Mon, 08 Jun 2026
Spruce Biosciences Announces Long-Term Tralesinidase Alfa Enzyme Replacement Therapy Data in Sanfilippo Syndrome Type B (MPS IIIB) Presented at the 18th International MPS Symposium - Business Wire

Mon, 08 Jun 2026
SPRB News | SPRUCE BIOSCIENCES INC (NASDAQ:SPRB) - ChartMill

Wed, 27 May 2026
Spruce Biosciences to Participate in Upcoming Conferences in June - Investing News Network

Tue, 26 May 2026
Spruce Biosciences (SPRB) grants director Keli Walbert 1,700 options - Stock Titan

Financial Analysis
Price to Book Value:
P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly.
Neutral
Price to Earnings:
PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS).
Underperform
Discounted cash flow:
DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows.
Outperform
Return on Assets:
ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit.
Underperform
Return on Equity:
ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency.
Underperform
Debt to Equity:
evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn.
Underperform
Stock Basics & Statistics
Exchange:
NASDAQ
Sector:
Healthcare
Industry:
Biotechnology
Shares Out 3 (M)
Shares Float 3 (M)
Held by Insiders 3.5 (%)
Held by Institutions 31 (%)
Shares Short 215 (K)
Shares Short P.Month 181 (K)
Stock Financials
EPS -35.82
EPS Est Next Qtrly 0
EPS Est This Year 0
EPS Est Next Year 0
Book Value (p.s.) 30.98
Profit Margin 0 %
Operating Margin 0 %
Return on Assets (ttm) -37.2 %
Return on Equity (ttm) -148.9 %
Qtrly Rev. Growth 0 %
Gross Profit (p.s.) -4.96
Sales Per Share 0
EBITDA (p.s.) -9.4
Qtrly Earnings Growth 0 %
Operating Cash Flow -29 (M)
Levered Free Cash Flow -13 (M)
Stock Valuations
PE Ratio -1.45
PEG Ratio 0
Price to Book value 1.67
Price to Sales 0
Price to Cash Flow -4.87
Stock Dividends
Dividend 0
Forward Dividend 0
Dividend Yield 0%
Dividend Pay Date Invalid DateTime.
Ex-Dividend Date Invalid DateTime.

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