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Spero Therapeutics, Inc. (SPRO)
2.67  -0.11 (-3.96%)    04-10 16:00
Open: 2.8
High: 2.8
Volume: 669,127
  
Pre. Close: 2.78
Low: 2.625
Market Cap: 155(M)
Technical analysis
2026-04-10 4:39:52 PM
Short term     
Mid term     
Targets 6-month :  3.27 1-year :  3.81
Resists First :  2.79 Second :  3.27
Pivot price 2.47
Supports First :  2.43 Second :  2.21
MAs MA(5) :  2.69 MA(20) :  2.48
MA(100) :  2.37 MA(250) :  2.14
MACD MACD :  0 Signal :  0
%K %D K(14,3) :  89.6 D(3) :  91.5
RSI RSI(14): 61.5
52-week High :  3.22 Low :  0.52
Price, MAs and Bollinger Bands

Price has closed below its short-term moving average. Short-term moving average is currently above mid-term; and above long-term moving average. From the relationship between price and moving averages: This stock is NEUTRAL in short-term; and BULLISH in mid-long term.
[ SPRO ] has closed below upper band by 19.9%. Bollinger Bands are 83% wider than normal. The large width of the bands suggest high volatility as compared to its normal range. The bands have been in this wide range for 2 days. This is a sign that the current trend might continue.

Stock Price Prediction
If tomorrow: Open lower Open higher
High: 2.8 - 2.82 2.82 - 2.83
Low: 2.59 - 2.61 2.61 - 2.62
Close: 2.64 - 2.67 2.67 - 2.69
Company Description

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying, developing, and commercializing treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include tebipenem pivoxil hydrobromide (HBr), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adults; SPR206, a direct acting IV-administered agent to treat MDR Gram-negative bacterial infections in the hospital; and SPR720, an oral antibiotic for the treatment of non-tuberculous mycobacterial pulmonary disease. It has license agreement with Meiji Seika Pharma Co., Ltd. to support the development of tebipenem HBr; license agreement with Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries; collaboration agreement with Bill & Melinda Gates Medical Research Institute to develop SPR720 for the treatment of lung infections caused by Mycobacterium tuberculosis; and license agreement with Vertex Pharmaceuticals Incorporated for patents relating to SPR720, as well as SPR719, an active metabolite. The company was founded in 2013 and is headquartered in Cambridge, Massachusetts.

Headline News

Wed, 08 Apr 2026
Spero Therapeutics (SPRO) price target decreased by 20.00% to 4.08 - MSN

Mon, 06 Apr 2026
SPRO Forecast, Price Target & Analyst Ratings | SPERO THERAPEUTICS INC (NASDAQ:SPRO) - ChartMill

Sat, 28 Mar 2026
Spero Therapeutics (SPRO) Earnings Turn Positive Challenging Bearish Profitability Narratives - simplywall.st

Thu, 26 Mar 2026
Spero Therapeutics Announces Fourth Quarter and Full Year 2025 Operating Results and Provides a Business Update - GlobeNewswire

Thu, 26 Mar 2026
Spero’s oral UTI antibiotic faces FDA decision on June 18 - Stock Titan

Wed, 11 Feb 2026
Spero Therapeutics: Tebipenem’s FDA Path Supports A Speculative Buy (NASDAQ:SPRO) - Seeking Alpha

Financial Analysis
Price to Book Value:
P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly.
Neutral
Price to Earnings:
PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS).
Neutral
Discounted cash flow:
DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows.
Underperform
Return on Assets:
ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit.
Outperform
Return on Equity:
ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency.
Outperform
Debt to Equity:
evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn.
Underperform
Stock Basics & Statistics
Exchange:
NASDAQ
Sector:
Healthcare
Industry:
Biotechnology
Shares Out 58 (M)
Shares Float 46 (M)
Held by Insiders 22.5 (%)
Held by Institutions 16.7 (%)
Shares Short 537 (K)
Shares Short P.Month 716 (K)
Stock Financials
EPS 0.15
EPS Est Next Qtrly 0
EPS Est This Year 0
EPS Est Next Year 0
Book Value (p.s.) 0.46
Profit Margin -108.2 %
Operating Margin -134.7 %
Return on Assets (ttm) -29.8 %
Return on Equity (ttm) -95.4 %
Qtrly Rev. Growth -59.6 %
Gross Profit (p.s.) -0.37
Sales Per Share 0.7
EBITDA (p.s.) -0.78
Qtrly Earnings Growth 0 %
Operating Cash Flow -28 (M)
Levered Free Cash Flow -7 (M)
Stock Valuations
PE Ratio 17.79
PEG Ratio 0
Price to Book value 5.68
Price to Sales 3.81
Price to Cash Flow -5.59
Stock Dividends
Dividend 0
Forward Dividend 0
Dividend Yield 0%
Dividend Pay Date Invalid DateTime.
Ex-Dividend Date Invalid DateTime.

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