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Spero Therapeutics, Inc. (SPRO)
1.19  -0.01 (-0.83%)    07-31 14:08
Open: 1.19
High: 1.2138
Volume: 500,601
  
Pre. Close: 1.2
Low: 1.17
Market Cap: 69(M)
Technical analysis
2026-07-31 1:47:54 PM
Short term     
Mid term     
Targets 6-month :  2.17 1-year :  2.73
Resists First :  1.85 Second :  2.33
Pivot price 1.4
Supports First :  1.08 Second :  0.89
MAs MA(5) :  1.18 MA(20) :  1.59
MA(100) :  2.37 MA(250) :  2.29
MACD MACD :  -0.4 Signal :  -0.3
%K %D K(14,3) :  8.4 D(3) :  8.7
RSI RSI(14): 21.7
52-week High :  3.07 Low :  1.08
Price, MAs and Bollinger Bands

Price has closed below its short-term moving average. Short-term moving average is currently below mid-term; and below long-term moving average. From the relationship between price and moving averages: This stock is BEARISH in short-term; and BEARISH in mid-long term.
[ SPRO ] has closed above bottom band by 29.0%. Bollinger Bands are 68.6% wider than normal. The large width of the bands suggest high volatility as compared to its normal range. The bands have been in this wide range for 11 days. This is a sign that the current trend might continue.

Stock Price Prediction
If tomorrow: Open lower Open higher
High: 1.22 - 1.23 1.23 - 1.23
Low: 1.17 - 1.17 1.17 - 1.18
Close: 1.19 - 1.2 1.2 - 1.21
Company Description

Spero Therapeutics, Inc. is a biopharmaceutical firm in the clinical development stage, primarily focused on discovering, advancing, and commercializing innovative treatments for multi-drug resistant (MDR) bacterial infections and rare diseases within the United States. The company's pipeline includes several key therapeutic candidates: tebipenem pivoxil hydrobromide (HBr), an oral carbapenem-class antibiotic designed to address complicated urinary tract infections (cUTIs), including pyelonephritis, in adult patients. SPR206, an intravenously administered agent specifically developed to combat MDR Gram-negative bacterial infections in hospital environments. SPR720, an oral antibiotic targeting non-tuberculous mycobacterial (NTM) pulmonary disease. Spero Therapeutics has also forged several strategic alliances: A licensing agreement with Meiji Seika Pharma Co., Ltd. supports the ongoing development of tebipenem HBr. A separate licensing deal with Everest Medicines grants rights for the development, manufacturing, and commercialization of SPR206 across Greater China, South Korea, and various Southeast Asian nations. The company collaborates with the Bill & Melinda Gates Medical Research Institute to advance SPR720 for treating lung infections caused by Mycobacterium tuberculosis. Furthermore, a licensing agreement with Vertex Pharmaceuticals Incorporated covers patents associated with SPR720 and its active metabolite, SPR719. Founded in 2013, Spero Therapeutics maintains its corporate headquarters in Cambridge, Massachusetts.

Headline News

Thu, 30 Jul 2026
Spero Therapeutics Inc (SPRO) Financial Health: Profitability & Balance Sheet Analysis - TradingKey

Tue, 28 Jul 2026
SPRO|Spero Therapeutics Inc|Price:1.195| - TradingKey

Mon, 27 Jul 2026
Spero's Phase 2-Ready Antibody Has a New Clinical Lead - Stock Titan

Sun, 19 Jul 2026
Enterprise value to EBITDA forward of Spero Therapeutics, Inc. – NASDAQ:SPRO - tradingview.com

Tue, 14 Jul 2026
Spero Therapeutics Secures $105 Million Royalty Financing to Advance SP001 and Extend Cash Runway Through Second Half of 2029 - Quiver Quantitative

Tue, 14 Jul 2026
Spero in-licenses Innovent’s antibody therapy (SPRO:NASDAQ) - Seeking Alpha

Financial Analysis
Price to Book Value:
P/BV, a ratio used to compare book value to its current market price, to gauge whether a stock is valued properly.
Neutral
Price to Earnings:
PE, the ratio for valuing a company that measures its current share price relative to its earnings per share (EPS).
Neutral
Discounted cash flow:
DCF, a valuation method used to estimate the value of an investment based on its expected future cash flows.
Underperform
Return on Assets:
ROA, indicates how profitable a company is in relation to its total assets, how efficiently uses assets to generate a profit.
Outperform
Return on Equity:
ROE, a measure of financial performance calculated by dividing net income by equity. a gauge of profitability and efficiency.
Outperform
Debt to Equity:
evaluate financial leverage, reflects the ability of equity to cover outstanding debts in the event of a business downturn.
Outperform
Stock Basics & Statistics
Exchange:
NASDAQ
Sector:
Healthcare
Industry:
Biotechnology
Shares Out 0 (M)
Shares Float 58 (M)
Held by Insiders 4.638e+007 (%)
Held by Institutions 22.4 (%)
Shares Short 1,830 (K)
Shares Short P.Month 0 (K)
Stock Financials
EPS 0
EPS Est Next Qtrly 0
EPS Est This Year 0
EPS Est Next Year 0
Book Value (p.s.) 0
Profit Margin 24.8 %
Operating Margin -2 %
Return on Assets (ttm) 921.7 %
Return on Equity (ttm) 12.9 %
Qtrly Rev. Growth 6.119e+007 %
Gross Profit (p.s.) -64.17
Sales Per Share 23.57
EBITDA (p.s.) 2.24295e+007
Qtrly Earnings Growth 0.2 %
Operating Cash Flow 0 (M)
Levered Free Cash Flow 7 (M)
Stock Valuations
PE Ratio 0
PEG Ratio 0
Price to Book value 0
Price to Sales 0.04
Price to Cash Flow 1.91
Stock Dividends
Dividend 0
Forward Dividend 2.11e+006
Dividend Yield 0%
Dividend Pay Date Invalid DateTime.
Ex-Dividend Date Invalid DateTime.

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